Sunday, March 31, 2013

Christians in Holy Land, Mideast celebrate Easter

JERUSALEM (AP) ? Catholics and Protestants flocked to churches to celebrate Easter on Sunday in the Holy Land and across the broader Middle East, praying, singing and rejoicing.

Some Mideast Christian communities are in a flux, while others feel isolated from their Muslim-majority societies. In places like Iraq, they have sometimes been the victims of bloody sectarian attacks.

At St. Joseph Chaldean Church in Baghdad, some 200 worshippers attended an Easter mass that the Rev. Saad Sirop led behind concrete blast walls and a tight security cordon. Churches have been under tighter security since a 2010 attack killed dozens.

"We pray for love and peace to spread through the world," said worshipper Fatin Yousef, 49, who arrived immaculately dressed for the holiday. She wore a black skirt, low-heeled pumps and a striped shirt and her hair tumbled in salon-created curls.

It was the first Easter since the election of Pope Francis and she and others expressed hope in their new spiritual leader. "We hope Pope Francis will help make it better for Christians in Iraq," she said.

In Jerusalem, Catholics worshipped in the church of the Holy Sepulcher, built on a hill where tradition holds that Jesus was crucified, briefly entombed and then resurrected. The cavernous, maze-like structure is home to different churches belonging to rival sects that are crammed into different nooks and even the roof.

Clergy in white and gold robes led the service held around the Edicule, the small chamber at the core of the church marking the site of Jesus' tomb. Many foreign visitors were among the worshippers.

"It's very special," said Arthur Stanton, a visitor from Australia. "It represents the reason why we were put on this planet, and the salvation that has come to us through Jesus."

Israel's Tourism Ministry said it expects some 150,000 visitors during holy week and the Jewish festival of Passover, which coincide this year. It is one of the busiest times of the year for the local tourism industry.

Protestants held Easter ceremonies outside Jerusalem's walled Old City at the Garden Tomb, a small, enclosed green area that some identify as the site of Jesus' burial. Another service was held at the Church of the Nativity in Bethlehem, Jesus' traditional birthplace.

Catholics and Protestants, who follow the new, Gregorian calendar, celebrate Easter on Sunday. Orthodox Christians, who follow the old, Julian calendar, will mark it in May.

There are no precise numbers on how many Christians there are in the Middle East. Census figures showing the size of religious and ethnic groups are hard to obtain.

Christian populations are thought to be shrinking or at least growing more slowly than their Muslim compatriots in much of the Middle East, largely due to emigration as they leave for better opportunities and to join families abroad. Some feel more uncomfortable amid growing Muslim majorities that they see as becoming more outwardly pious and politically Islamist over the decades.

The situation for some Mideast Christians is in flux.

In Syria, Christians, who make up some 10 percent of the country's 23 million people, have mostly stayed on the sidelines of the two-year civil war. While outraged by the regime of Bashar Assad's brutal efforts to quash the opposition, they are equally frightened by the Islamist rhetoric of many rebels and their heavy reliance on extremist fighters.

Christians make up some 10 percent of Egypt's 85 million people. Human rights groups say the police under former authoritarian leader Hosni Mubarak rarely took the needed steps to prevent flare-ups of violence against Christians, a situation that persisted since he was overthrown in 2011. The rise of Islamists in Egypt has emboldened extremists to target churches and Coptic property, leading to a spike in attacks and sometimes unprecedented steps like the evacuation of entire Christian populations from villages.

In Libya, most Christians are Egyptian laborers who are working in the oil-rich country. Tensions rose last month after assailants torched a church in the eastern city of Benghazi and militias arrested some 100 Christians, mostly Egyptian, accusing them of proselytizing.

In Iraq, Christians have suffered repeated attacks by Islamic militants since the 2003 U.S.-led invasion, and hundreds of thousands have left the country. Church officials estimate that the Christian communities have shrunk by at least half. The worst attack was at Baghdad's soaring Our Lady of Salvation church in October 2010 that killed more than 50 worshippers and wounded scores of others.

There currently are an estimated 400,000 to 600,000 Christians in Iraq, with most belonging to ancient eastern churches. Some two-thirds of Iraq's Christians are Catholics of the Chaldean church and the smaller Assyrian Catholic church. Members of both churches chant in dialects of ancient Aramaic, the language that Jesus spoke.

Yousef, the worshipper in Baghdad, said lingering fear pushed her to send her son to live with relatives in Arizona last year. Yousef said she was arranging for her other daughter and son to immigrate.

"There's still fear here, and there's no stability in this country," she said.

Iraqi officials have made efforts to secure churches since the violence of 2010.

High blast walls topped with wire netting and barbed wire surrounded the St. Joseph Church in Baghdad's middle-class district of Karradeh. Four Iraqi Christian volunteers stood at the church entrance, double-checking the people entering. And blue-khaki clad Iraqi police guarded roads surrounding the church and checked papers of passers-by as worshippers filed inside.

White-robed church volunteers marched down the church aisle behind Father Sirop, who waved incense and chanted in the white-painted church adorned with three ornate chandeliers and a series of simple paintings illustrating the life of Christ.

Worshippers stood for lengthy passages of Sirop's mass, at one point bursting into applause when he told them, "Celebrate! You are Christians!"

___

Hadid reported from Baghdad. Follow Hadid on twitter.com/diaahadid and Goldenberg on twitter.com/tgoldenberg

Source: http://news.yahoo.com/christians-holy-land-mideast-celebrate-easter-143435186.html

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Saturday, March 30, 2013

Obama takes jobs pitch to Miami

President Barack Obama will promote a plan to create jobs by attracting private investment in highways and other public works during a visit Friday to a Miami port, the White House said.

The president will flesh out details of his proposals in a speech at the port, which is undergoing $2 billion in upgrades paid for with government and private money. Obama, in the quick trip to South Florida, will try to show that the economy remains his top priority in the midst of high-profile campaigns on immigration reform and gun control.

Among the proposals Obama will call for:

?Higher caps on "private activity bonds" to encourage more private spending on highways and other infrastructure projects. State and local governments use the bonds to attract investment.

?Giving foreign pension funds tax-exempt status when selling U.S. infrastructure, property or real estate assets. U.S. pension funds are generally tax exempt in those circumstances. The administration says some international pension funds cite the tax burden as a reason for not investing in American infrastructure.

?$4 billion in new spending on two infrastructure programs that award loans and grants.

?A renewed call for a $10 billion national "infrastructure bank" ? a proposal from his first term that gained little traction.

The president made private-sector infrastructure investment a key part of the economic agenda he rolled out in his State of the Union address last month. He also called in his address for a "Fix-It-First" program that would spend $40 billion in taxpayer funds on urgent repairs.

Obama's focus on generating more private sector investment underscores the tough road new spending faces on Capitol Hill, where Republican lawmakers often threaten to block additional spending unless it is paid for by tax cuts or other measures.

Any increased spending associated with the proposals Obama was outlining Friday would not add to the deficit, a senior administration official said. The official was not authorized to discuss the plan in advance of Obama's announcement and spoke on condition of anonymity.

The official did not detail how the costs would be paid for, saying only that more information would be included in the president's budget.

Obama will release his budget April 10.

???

Follow Josh Lederman on Twitter: http://twitter.com/joshledermanAP

Follow Julie Pace on Twitter: http://twitter.com/jpaceDC

Also Read

Source: http://news.yahoo.com/obama-pitch-more-jobs-public-142807078.html

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GameStop says demand hit as customers await new console launches

(Reuters) - GameStop Corp, the world's largest retailer of video game products, warned of weak sales this year, as customers delay purchases ahead of the launch of next-generation gaming consoles.

Comparable store sales are likely to fall by between 5.5 percent and 8 percent in the current quarter, the company warned.

Full-year sales are forecast to remain flat or fall by up to 8 percent, implying a revenue of between $8.18 billion and $8.89 billion. Analysts expect $8.86 billion on average, according to Thomson Reuters I/B/E/S.

GameStop's full-year earnings forecast also lagged analysts' estimates by a sizeable margin. It sees full-year earnings at $2.75-$3.15 per share, while analysts had estimated $3.40 per share.

The video game industry is anticipating a strong finish to 2013 with the release of Grand Theft Auto V and the launch of at least one next-generation console by the holidays.

As a result, GameStop expects the first half of the year to be challenging as consumers postpone purchases leading up to the fourth quarter console launch.

Sony Corp said last month it would launch its next-generation PlayStation this year, its first video game console in seven years. Microsoft Corp is also expected to unveil the successor to its Xbox 360 later this summer.

Sales of traditional video game products such as consoles have been pressured globally by the rising popularity of online games as enthusiasts spend more time on tablets and phones.

U.S. sales of videogame hardware and software fell 25 percent in February, following a month-over-month downward trend that has continued since last year, according to a report by market research firm NPD.

Games software sales were down 27 percent during the same month, the report added.

GameStop has weathered the trend by focusing on selling new and used games to console owners and expanding its digital and mobile offerings, including the sale of iOS and Android devices in some stores.

The company said total revenue fell marginally in the fourth quarter to $3.56 billion.

Net income rose $261.1 million, or $2.15 per share, from $174.7 million, or $1.27 cents per share a year earlier.

Adjusted for the deferral of digital revenue and other items, the company's earnings were $262.3 million, or $2.16 per share.

Analysts on average expected earnings of $2.09 per share on revenue of $3.45 billion for the fourth quarter.

In January, GameStop cut its same-store sales forecast for the fourth quarter after customer traffic shrank over the holiday season.

The company's shares were trading up 2 percent at $26.92 in early morning trade on the New York Stock Exchange on Thursday.

(Reporting by Neha Alawadhi in Bangalore; Editing by Sreejiraj Eluvangal)

Source: http://news.yahoo.com/gamestop-posts-higher-fourth-quarter-profit-124533295--sector.html

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Friday, March 29, 2013

Exclusive: Indonesia's CT Corp proposes all-cash deal for Bakrie's media unit

By Janeman Latul and Randy Fabi

TANJUNG BENOA, Indonesia (Reuters) - CT Corp, one of Indonesia's emerging conglomerates, has proposed an all-cash deal for a controlling stake in media firm PT Visi Media Asia , valued at up to $1.8 billion, to strengthen its position in the media business in Southeast Asia's biggest economy.

The founder and chairman of CT Corp, Chairul Tanjung, told Reuters that his firm wanted to purchase Visi Media, a unit of Indonesia's powerful Bakrie family, without any partners.

"We are one of the preferred bidders. Our proposal is we want to buy it all ... my pocket is still deep," the 51-year-old billionaire said in his hotel room on the resort island of Bali, shortly after meeting with the president and cabinet ministers in his role as head of the president's economic advisory body.

"(It is) only us that can pay cash one hundred percent ... but the deal is not done yet."

CT Corp is already a major player in the Indonesian media business and controls two local TV stations. Tanjung said he would take out a new loan to buy the Visi Media stake. He declined to say how much the company would borrow for the deal.

This is the first time any bidder has publicly announced that it was offering to buy the company.

Indonesia's politically influential Bakrie family has been in talks to sell its majority interest in Visi Media to help finance a plan to buy back coal assets from London-listed Bumi Plc , sources with direct knowledge have said.

The Bakries are offering around a 51 percent stake in Visi Media, which the family controls via its vehicle CMA Indonesia. The process has been going on for the past three months with local bidders, including CT Corp and MNC Group, the sources said.

The Bakries had been looking for a valuation of $1.2 billion to $2 billion for the unit, although Visi Media's current market capitalization is only around $800 million, the sources said.

Visi Media has two national TV stations and a news website.

The sources said the stake would be worth up to $1.8 billion.

Tanjung, who trained as a dentist before becoming a businessman, also plans to build a $3 billion theme park on Indonesia's Java island and make it one of the biggest theme parks in Southeast Asia when it opens in 2016.

"We will build a city, not only a theme park, as I want to make many Indonesians feel happy," Tanjung said, adding that the land for the park would be around 200 hectares and the construction would start by the end of this year.

The group, which was founded by Tanjung, currently operates two theme parks and has plans to add another 20 theme parks across Indonesia over the next few years.

Tanjung is Indonesia's fifth-richest man with a net worth around $3.4 billion as of march, according to Forbes.

(Editing by Jonathan Thatcher and Chris Gallagher)

Source: http://news.yahoo.com/exclusive-indonesias-ct-corp-proposes-cash-deal-bakries-041447140--finance.html

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92% The Gatekeepers

All Critics (71) | Top Critics (30) | Fresh (65) | Rotten (6)

The film and its talking head participants paint the picture in both broad strokes and fine detail.

Whatever one's political stripe regarding Israel, it's hard to dispute the impressions and perspective of the film's six eyewitnesses.

The level of candor here may not satisfy hard-liners of either stripe, but it can help viewers begin to formulate new questions about the philosophical, strategic and moral challenges of conflict, in particular "wars on terror."

Ultimately the movie feels evasive, and its flashy, digitally animated re-creations of military surveillance footage unpleasantly evoke the Call of Duty video games.

It offers startlingly honest insight into the Israeli-Palestinian conflict from some of those who called the shots.

As a political testament, the result is revealing and important.

Moreh employs a direct interviewing style, reminiscent of Errol Morris' work, to get the men to talk about their days leading Shin Bet.

Moreh gets some startling confessions and insights from each man but also misses the opportunity to truly challenge his subjects on their regard for democracy, basic human rights and their own accountability.

Director Dror Moreh doesn't rest on his scoop

A powerful look inside the Israeli defense establishment

A deadly serious and detailed examination of and meditation upon the Israeli-Palestinian conflict, The Gatekeepers makes no attempt to find a silver lining.

The rule of surveillance is to keep quiet and let others do the talking. The Oscar-nominated documentary The Gatekeepers flips the script, to astonishing effect, giving voice to the retired directors of Shin Bet, Israel's domestic intelligence agency.

An up-close and personal look at the psychology of war -- their war and, by extension, all war.

A riveting firsthand account of how legitimate security concerns can lead to policies considered extreme and even immoral by the people administering them.

Extraordinary...not only an engrossing first-hand account of Israel's Palestinian policies over time, but one that may have lessons to teach both Israeli leaders and other nations confronting those they identify as terrorists.

Unprecedented and deeply unsettling, it offers little hope for a lasting peace in that war-torn region.

For its candor and impact, deserves to be seen and discussed.

An often remarkable Israeli documentary about Shin Bet, the country's internal security agency.

Source: http://www.rottentomatoes.com/m/the_gatekeepers_2012/

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PFT: Palmer reportedly prefers release to paycut

New York Jets v Buffalo BillsGetty Images

Former NFL quarterback Jeff Garcia working with Jets starter-for-now Mark Sanchez seems like a legitimate opportunity for a man well-versed in the West Coast Offense to share his wisdom.

Throw in JaMarcus Russell, and it sounds like a punch line that?s looking for a joke.

But Garcia said he was impressed with the work Sanchez was doing, as he gets used to the changes new offensive coordinator Marty Mornhinweg is bringing to the Jets.

?He?s doing an excellent job ? the progress Mark has made over the past three weeks is definitely very positive,? Garcia told Jim Corbett of USA Today. ?It shows Mark is committed to bettering himself and getting himself more mentally prepared.

?

?The most important thing for Mark is to take that tough season last year as a learning experience from the standpoint of how he can get better and give his team the best chance to win. That has to be done in terms of being confident in his ability to run this system and speak the language correctly. So now when he takes the field in OTAs, he?ll be in that much more comfortable of a place.?

Garcia?s a good tutor for the system, and he threw for career-best numbers under Mornhinweg?s tutelage in San Francisco in 2000.

?Marty and I communicated a few weeks ago [about] what he?d like to introduce to Mark,? Garcia said. ?Mark is definitely getting more comfortable speaking the West Coast terminology. He had a brief glimpse of the West Coast system at USC.

?The toughest thing is this will be Mark?s third offensive coordinator in six seasons. The guy has had to learn a new system just about every other year. From a consistency standpoint, that just doesn?t translate to success in the NFL. You really need to be secure in what you?re doing mentally in order to compete at the highest level.?

Speaking of which, Garcia said Russell?s trying to get in shape for a pro day in a month or so, hoping to get another chance.

?Granted his back is against the wall,? Garcia said of the former first-overall pick. ?This is a situation where if he doesn?t do it now, it may never happen. But if you look at where he was two months ago to where he is today, he?s come a long way in demanding more out of himself than he ever did.?

If he had done that the first time through, he might not be a reclamation case.

Source: http://profootballtalk.nbcsports.com/2013/03/28/report-carson-palmer-may-want-to-play-for-less-elsewhere-than-take-paycut-with-raiders/related/

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Guitar maker Gibson buys majority stake in TEAC, develops taste for electronica

US guitarmaker Gibson gets into the electronics business, buys majority stake in TEAC

That gruff American rocker, Gibson Guitar, has gotten tired of its old life. Instead of just suing copycats and putting out the occasional robot axe, it's now looking to diversify, having spent $52 million on a 54 percent stake in Japanese firm TEAC. The last we heard from TEAC, it was making things like headphones and retro-styled radios, which maybe gives us a hint as to where this new partnership is headed. After all, it's not like the path between music brand and consumer electronics hasn't been trodden to a pulp already.

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Source: AV Watch (Japanese)

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/5IyNv7ea3Es/

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Friday, March 15, 2013

INSIGHT-Mugabe takes on Zimbabwe's Generation X

By Cris Chinaka

BULAWAYO, Zimbabwe (Reuters) - It could be a scene from any African mobile phone ad: flanked by two mohawked teenagers and shuffling stiffly to a pulsing hip-hop beat, an old man puts a phone to his ear and addresses a young lady with an awkward "What's up?"

But the ageing, suited star of "Getting Connected" is Zimbabwean president Robert Mugabe and the message is political not commercial: the veteran leader is making a big pitch for the youngsters who have little time for his long speeches.

However desperate it may look - Mugabe is an 89-year-old social conservative who prefers choral arias to hip-hop - the video is a sign of the importance given to the generation of Zimbabweans born after the liberation struggle.

This year, for the first time since independence from Britain in 1980, more than half the 13 million population are 'Born Frees', offspring of the nation that emerged from the shackles of white-minority rule in the then-Rhodesia. The median age is 33, according to the National Statistics Office.

An election due this year, with youth and technology loosely pitted against history and conservatism, will serve as an important barometer of whether Africa is moving on from an era in which anti-colonialism holds sway over its politics.

It also has important lessons for South Africa's ruling African National Congress, which faces its own demographic day of reckoning in a decade, having only won its struggle against the white-minority apartheid government in 1994.

On paper, Morgan Tsvangirai, Mugabe's 61-year-old rival, appears better placed to tap into a social group desperate for jobs and leadership change to mend a limping economy.

A 2000-2008 economic crisis blamed largely on Mugabe's policies forced a quarter of Zimbaweans to leave the country. HIV/AIDS and malnutrition are among factors contributing to life expectancy that is below the sub-Sahara average - 50 versus 54, according to the World Bank.

"The future lies in dumping this grandfatherly generation that came to power before many of us were born," said 27-year-old engineering graduate Mthulisi Mpofu, warming himself by a fire in a thatched hut near the second city of Bulawayo.

"They are old and tired and have nothing to offer us. If the youth does the right thing, I don't see how we are not going to have a new government, new policies and jobs."

FRUSTRATION

However, Mugabe's liberation generation ZANU-PF party is fighting hard and - in the absence of any reliable opinion polls - the outcome of a general election is hard to predict.

Mpofu is one of over 150,000 high school and college graduates joining the job market annually, the product of huge investment by Mugabe in education after 1980 that is now coming up against one of the world's highest unemployment rates.

On average, just 20,000 graduates will manage to find a formal job each year; the rest will join the 80 percent of workers sitting idle and frustrated - an affront to a nation that claims one of Africa's highest literacy rates.

But it is far from given that the potentially huge numbers of disenchanted youngsters will come out to oppose Mugabe as he seeks to extend his 33 years in power.

A million or more are estimated to be working - in most cases illegally - in South Africa and will either be unable to return home to register or reluctant to risk signing up at embassies and consulates in Zimbabwe's neighbour.

As a result, local rights groups working to promote a free and fair vote after three violent and disputed elections estimate that only 20 percent of those on the current voters' roll are under 35.

In Harare and Bulawayo, potential new voters are being turned off by the bureaucracy of a registration process that requires them to present a national identity card and utility bill under a family name proving residence at a given address.

"This whole system is designed to frustrate people," said Lawrence Fakazi, 23, who queued for two hours with friends in Harare before giving up after being shunted from one office to another. "We are not going to bother again."

In the countryside the system is even more onerous, requiring a testimonial from a village head to confirm a new voter's address, a step that raises suspicions ZANU-PF officials are blocking supporters of Tsvangirai's MDC.

The end result is widespread youth apathy.

"Although we are the biggest victim of bad governance, the truth is our generation is also not committed to politics in the same manner that the old generation is," Mpofu said.

GENERATION X-1G

The MDC has also fallen short of its promises, failing to set up youth voters' clubs promised three years ago apparently for fear of exposing its plans and ideas to rivals.

Shifting the blame, MDC officials say ZANU-PF is at fault for making the registration process deliberately clunky, especially for a generation hooked on Facebook and Twitter.

"ZANU-PF is working to stifle the registration to avoid being overrun at the elections," spokesman Douglas Mwonzora said. "Zimbabwe is going through both a political and generation change in these elections."

Instead, the push to mobilise voters is falling to rights groups trying to energise people with text messages, radio jingles and website ads, riding on a doubling in the use of new media and social media since the last elections in 2008.

Latest government figures show that 90 percent of Zimbabwe's 13 million people now use mobile phones and Internet users have more than doubled to 4.5 million people in the past year.

Typical of the trend is a coalition of 10 pro-democracy youth groups called X-1G (www.x1g.org) asking first-time voters to be the "political game changers".

"We are a non-partisan organisation but our view is that the young now constitute a majority of the population and must assume some big responsibility in how the country is governed," X-1G activist Tawanda Chimhini said.

FIGHTING BACK

ZANU-PF is not standing idle. It has been offering cheap business start-up loans of $20,000 to youth groups and promising opportunities in foreign firms forced to sell 51 percent of their shares to locals under a black economic empowerment push.

Spearheading the drive is the young and tech-savvy ZANU-PF minister Saviour Kasukuwere, nicknamed Tyson for his combative style. For most young Zimbabweans, Kasukuwere's creaseless visage and gleaming smile stand out starkly against a ZANU-PF gerontocracy in which even Mugabe has confessed to feeling lonely because so many of his comrades have died.

Young voters are generally unimpressed by ZANU-PF's fondness for 1970s liberation war history lessons, recalling instead hyperinflation of 500 billion percent, food shortages and 4,000 dead from cholera at the nadir of the economic crisis in 2008.

"Nothing is given, but I think the party that is able to motivate its supporters and to win the new young voters stands to win the elections," said Eldred Masunungure, a University of Zimbabwe political science professor.

Source: http://news.yahoo.com/insight-mugabe-takes-zimbabwes-generation-x-074011473.html

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Militants disguised as cricketers attack Kashmir police camp

SRINAGAR, India (Reuters) - Two militants disguised as cricketers opened fire with automatic rifles on a paramilitary camp on the Indian side of the disputed region of Kashmir on Wednesday, killing five Indian personnel and wounding five, police said.

The militants were killed in a gunfight at the Central Reserve Police Force (CRPF) base just outside the restive city of Srinagar, under curfew for much of the last few weeks following protests and clashes with police.

Jammu and Kashmir state Chief Minister Omar Abdullah, describing the assault as a "suicide attack", said three civilians were also wounded.

"A division of the CRPF was deployed at a camp here and children were playing cricket in the field when two militants fired grenades and attacked our division," Abdul Gani Mir, Inspector General of Police, told Reuters TV. "We have lost five of our CRPF personnel who gunned down the two militants."

There was no immediate claim of responsibility for the attack. Mir said initial investigations suggested the militants belonged to the Pakistan-based Lashkar-e-Taiba group, which has a history of targeting civilians and the military in India.

Police said the attack began when the gunmen got out of a car outside a school near the camp and, disguised in cricket gear, walked across the school playing field to the camp and shot a sentry dead before firing indiscriminately into the base.

Militants often attacked security bases in Kashmir during the 1990s, when there was a full-blown insurgency against Indian rule in a region over which India and Pakistan fought two of their three wars. But there have been very few in recent years.

Tensions have been running high in Srinagar since last month, when India hanged a Kashmiri man for an attack on the country's parliament in 2001. The authorities have sought to quash clashes between protesters and police by imposing curfews.

(Reporting by Fayaz Bukhari; Additional reporting by Ashok Pahalwan in JAMMU, India; Writing by John Chalmers; Editing by Nick Macfie)

Source: http://news.yahoo.com/five-killed-militant-attack-kashmir-police-camp-072724485.html

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Monday, March 11, 2013

93% Amour

February 25, 2013:
RT's Oscar Picks 2013 - Results
We at Rotten Tomatoes freely admit we're not the world's greatest Oscar prognosticators. Still, we...
February 24, 2013:
2013 Academy Awards Winners
The 85th Academy Awards are scheduled to take place on Sunday, February 24th in Los Angeles, and if...

Source: http://www.rottentomatoes.com/m/771307454/

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Sunday, March 10, 2013

Hagel Reacts to Kabul Suicide Bomber During Visit | Baby Boomer ...

Chuck Hagel is definitely off to a running start as the newest US Secretary of Defense. He is the 24th to hold that position, and his political affiliation is Republican. He is 66 years old, so definitely a baby boomer. He knows what war is, so going to a country where there is war is nothing new to him.

Since this suicide bombing referred to in the video, he has had news conferences with himself and President Hamid Karzai cancelled. It is going to be a rough time when coalition forces leave Afghanistan. We have been there for 12 years now. That is just incredible.

Will US forces leave in 2014? What sort of country will we leave? I am sure that there is not one person in the US who either is close to someone who has served in the military in Afghanistan of is a family member. Several do not come home the same. Is the toughness that the veterans of WW1 and WW2 gone? Or did they come home to a different America? Now so many come home to unemployment, they have injuries that VA benefits barely cover, and they have emotional trouble that most Veterans probably had but were not really focused on.

I wish everyone the best who is effected world wide by this war in the Mideast. Will it ever end? I highly doubt it. Will we get our troops out? Yes, but for how long I am not sure.

*Several statements are just my opinions, and not from any news source.

However, I did use The Washington Post for some of the information on this posting.

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Tags:afghanistan,baby boomer,chuck hagel,coalition forces,hamid karzai,kabul,news conferences,secretary of defense,suicide bomber,suicide bombing,washington post

Source: http://www.babyboomernewsletter.com/hagel-reacts-to-kabul-suicide-bomber-during-visit/

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Tech vs. society: Why the Unabomber still makes us think

"I started corresponding with him in 2003," David Skrbina said of his prison pen pal, the author he helped get published five years ago. "In 2005, we had enough material in the essays and the letters he had written during incarceration that I suggested that we publish them in a book."

The content was there ? cogent, academic pieces on how technology is alienating us from the natural world, psychically, psychologically and physiologically, damaging us, separating us from our evolutionary nature. Alas, the publishers were not.

"We spent two years trying to find an American publisher and nobody would take it. The original contact person was always very interested in the new book. They would go away and they would come back a few weeks later and say, 'Our management has decided we cannot pursue this project.'"

Having a friend behind bars is never easy. Being a self-appointed literary agent is always a challenge. But it's even tougher when your penitentiary-bound writer is a notorious domestic terrorist and enemy of the state who calls for the destruction of civilization.

Skrbina's pen pal is Ted "Unabomber" Kaczynski, the radical environmentalist and anti-civ guru who is serving life in a federal supermax prison for killing three people and injuring 23 in a campaign that ran nearly two decades. His method? He sent 16 mail bombs to universities and airlines (hence "una") between 1978 and 1995.

Although best known for coercing the New York Times and the Washington Post into publishing his 3,500-word manifesto, "Industrial Society and its Future" in 1995, Kaczynski continues to write from prison and remains an influential thinker in anarchist Deep Green Resistance circles, activists who believe global warming is real, and are willing to protect the planet by any means necessary.

After a brief run from a French publisher under a different title in 2008, "Technological Slavery: The Collected Writings of Theodore J. Kaczynski, a.k.a. 'The Unabomber'" eventually found a publisher in the United States ? the alternative, independent Feral House ? and the book hit American shelves in 2010. Skrbina penned the intro.

Kaczynski's ideas about the dehumanizing and devastating effects of industrialization and technology on humanity and the planet are often overshadowed by the murders he committed while single-handedly trying to jumpstart a revolution from his remote cabin in Montana. That split was manifest during "What Can We Learn From the Unabomber?", a packed panel discussion Friday at South by Southwest in Austin, between Skrbina, a philosophy professor at the University of Michigan and Peter Ludlow, a philosophy professor at Northwestern.

Both thinkers identify themselves as tech skeptics, though Ludlow argues that we have nothing to learn from the Unabomber or his manifesto.

It was a surreal debate ? 400 or 500 technorati packed into a room, eager to discuss the works of a man who thinks they're causing the world's demise. Indeed, it was hard to argue when Ludlow said the only reason there were more than five people in attendance was because Kaczynski "had killed a bunch of people." Ludlow went on to deploy a machine-gun volley of assaults on Kaczynski's logic and personal credibility, ranging from the manifesto's bizarre slags (leftists are effeminate?) to a comparison of Kaczynski to cannibalistic serial killer Jeffrey Dahmer.

Though both men could be called crazy, Kaczynski believed he was engaged in political action. Dahmer was just hungry.

Talking with NBC News, Skrbina allowed that people are interested in Kaczynski because he's a killer ? a very intelligent killer who went to Harvard at 16 and got a Ph.D. in mathematics at 25. Killer or not, Kaczynski's ideas have a rich and textured historical heritage, he added.

Skrbina points to Jacques Ellul, the 20th Century French philosopher concerned with the tyranny of tech over humanity, credited with coining the phrase, "Think globally, act locally." Technological skepticism goes back to Plato and Aristotle, continues through Samuel Butler and Martin Heidegger and goes today with essayists and artists such as Derrick Jensen and Stephanie McMillan.

Skrbina minimizes his own exposure to technology. "I don't do Facebook. I do email. I do minimal Web surfing, word processing." He has a TV, but with rabbit ears.

While partly sympathetic to Kaczynski's beliefs, Skrbina's not in this for the friendship, describing the forcibly retired Unabomber as a prickly, difficult person. Skrbina's a philosopher. This is about ideas.

"We have very serious problems that need to be discussed and if he can be one more cause to discuss those problems then we should take advantage and do it."

So ? and this is beyond uncomfortable to admit ? it may be that our tech-addled American brains need acts of violence and mayhem to draw our attention from our smartphone screens. These unforgivable acts are getting people to talk about big-picture issues such as the role of tech in society and the real threats to our planet. The killer is in prison and his killings have ceased. Now that he has spurred a debate about our future, what are we as a species going to do?

Helen A.S. Popkin goes blah blah blah about the Internet. Tell her to get a real job on Twitterand/or Facebook.

Source: http://www.nbcnews.com/technology/technolog/tech-vs-society-why-unabomber-still-makes-us-think-1C8780230

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Age Of Empires II HD Is Coming To Steam, And We?re ?Reeeaady?

Screen Shot 2013-03-08 at 10.28.41 AMGaming isn’t quite cyclical, thought it would seem that the big trend this winter is to remake old-school games from the 90′s for newer platforms. EA just released a brand new version of a personal childhood favorite, SimCity, and now it would appear that Age Of Empires II HD is coming to Steam’s platform. Steam is an online game seller that acts quite a bit like an App Store for PC game titles. The company has evolved past the desktop to mobile apps, as well as offering Windows non-gaming apps, but remains focused on bringing the best of gaming to the cloud. That said, Age Of Empires II HD will be available exclusively on Steam starting on April 9, with a price tag of $19.99. However, those who are itching with anticipation can pre-order and start playing on April 5, with a 10 percent discount. The game was originally developed by Ensemble Studios and published by Microsoft, but unfortunately Ensemble is no longer assembling. Instead, Hidden Path Entertainment, the same folks that developed Counter Strike: Global Offensive, have developed this iteration of the classic game. Age Of Empires is a real-time strategy game that lets users build civilizations and defend them against other countries and their settlements. The Steam version supports 1080p multi-monitor play, and it includes all the same single-player campaigns from the original game, along with the Conquerors expansion. Steam will also bring its own leaderboards, achievements, and Steam Cloud support to the title. To enjoy the nostalgic magic, the game requires Windows XP and later, 1.2GHz CPU, 1GB of RAM and a graphics card capable of DirectX 9. [via Slashgear]

Source: http://feedproxy.google.com/~r/Techcrunch/~3/hXaoMFizC2U/

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Saturday, March 9, 2013

Long predicted atomic collapse state observed in graphene

Friday, March 8, 2013

The first experimental observation of a quantum mechanical phenomenon that was predicted nearly 70 years ago holds important implications for the future of graphene-based electronic devices. Working with microscopic artificial atomic nuclei fabricated on graphene, a collaboration of researchers led by scientists with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have imaged the "atomic collapse" states theorized to occur around super-large atomic nuclei.

"Atomic collapse is one of the holy grails of graphene research, as well as a holy grail of atomic and nuclear physics," says Michael Crommie, a physicist who holds joint appointments with Berkeley Lab's Materials Sciences Division and UC Berkeley's Physics Department. "While this work represents a very nice confirmation of basic relativistic quantum mechanics predictions made many decades ago, it is also highly relevant for future nanoscale devices where electrical charge is concentrated into very small areas."

Crommie is the corresponding author of a paper describing this work in the journal Science. The paper is titled "Observing Atomic Collapse Resonances in Artificial Nuclei on Graphene." Co-authors are Yang Wang, Dillon Wong, Andrey Shytov, Victor Brar, Sangkook Choi, Qiong Wu, Hsin-Zon Tsai, William Regan, Alex Zettl, Roland Kawakami, Steven Louie, and Leonid Levitov.

Originating from the ideas of quantum mechanics pioneer Paul Dirac, atomic collapse theory holds that when the positive electrical charge of a super-heavy atomic nucleus surpasses a critical threshold, the resulting strong Coulomb field causes a negatively charged electron to populate a state where the electron spirals down to the nucleus and then spirals away again, emitting a positron (a positively?charged electron) in the process. This highly unusual electronic state is a significant departure from what happens in a typical atom, where electrons occupy stable circular orbits around the nucleus.

"Nuclear physicists have tried to observe atomic collapse for many decades, but they never unambiguously saw the effect because it is so hard to make and maintain the necessary super-large nuclei," Crommie says. "Graphene has given us the opportunity to see a condensed matter analog of this behavior, since the extraordinary relativistic nature of electrons in graphene yields a much smaller nuclear charge threshold for creating the special supercritical nuclei that will exhibit atomic collapse behavior."

Perhaps no other material is currently generating as much excitement for new electronic technologies as graphene, sheets of pure carbon just one atom thick through which electrons can freely race 100 times faster than they move through silicon. Electrons moving through graphene's two-dimensional layer of carbon atoms, which are arranged in a hexagonally patterned honeycomb lattice, perfectly mimic the behavior of highly relativistic charged particles with no mass. Superthin, superstrong, superflexible, and superfast as an electrical conductor, graphene has been touted as a potential wonder material for a host of electronic applications, starting with ultrafast transistors.

In recent years scientists predicted that highly-charged impurities in graphene should exhibit a unique electronic resonance ? a build-up of electrons partially localized in space and energy ? corresponding to the atomic collapse state of super-large atomic nuclei. Last summer Crommie's team set the stage for experimentally verifying this prediction by confirming that graphene's electrons in the vicinity of charged atoms follow the rules of relativistic quantum mechanics. However, the charge on the atoms in that study was not yet large enough to see the elusive atomic collapse.

"Those results, however, were encouraging and indicated that we should be able to see the same atomic physics with highly charged impurities in graphene as the atomic collapse physics predicted for isolated atoms with highly charged nuclei," Crommie says. "That is to say, we should see an electron exhibiting a semiclassical inward spiral trajectory and a novel quantum mechanical state that is partially electron-like near the nucleus and partially hole-like far from the nucleus. For graphene we talk about 'holes' instead of the positrons discussed by nuclear physicists."

To test this idea, Crommie and his research group used a specially equipped scanning tunneling microscope (STM) in ultra-high vacuum to construct, via atomic manipulation, artificial nuclei on the surface of a gated graphene device. The "nuclei" were actually clusters made up of pairs, or dimers, of calcium ions. With the STM, the researchers pushed calcium dimers together into a cluster, one by one, until the total charge in the cluster became supercritical. STM spectroscopy was then used to measure the spatial and energetic characteristics of the resulting atomic collapse electronic state around the supercritical impurity.

"The positively charged calcium dimers at the surface of graphene in our artificial nuclei played the same role that protons play in regular atomic nuclei," Crommie says. "By squeezing enough positive charge into a sufficiently small area, we were able to directly image how electrons behave around a nucleus as the nuclear charge is methodically increased from below the supercritical charge limit, where there is no atomic collapse, to above the supercritical charge limit, where atomic collapse occurs."

Observing atomic collapse physics in a condensed matter system is very different from observing it in a particle collider, Crommie says. Whereas in a particle collider the "smoking gun" evidence of atomic collapse is the emission of a positron from the supercritical nucleus, in a condensed matter system the smoking gun is the onset of a signature electronic state in the region nearby the supercritical nucleus. Crommie and his group observed this signature electronic state with artificial nuclei of three or more calcium dimers.

"The way in which we observe the atomic collapse state in condensed matter and think about it is quite different from how the nuclear and high-energy physicists think about it and how they have tried to observe it, but the heart of the physics is essentially the same," says Crommie.

If the immense promise of graphene-based electronic devices is to be fully realized, scientists and engineers will need to achieve a better understanding of phenomena such as this that involve the interactions of electrons with each other and with impurities in the material.

"Just as donor and acceptor states play a crucial role in understanding the behavior of conventional semiconductors, so too should atomic collapse states play a similar role in understanding the properties of defects and dopants in future graphene devices," Crommie says.

"Because atomic collapse states are the most highly localized electronic states possible in pristine graphene, they also present completely new opportunities for directly exploring and understanding electronic behavior in graphene."

###

DOE/Lawrence Berkeley National Laboratory: http://www.lbl.gov

Thanks to DOE/Lawrence Berkeley National Laboratory for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127212/Long_predicted_atomic_collapse_state_observed_in_graphene

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NASA satellite sees Sandra strengthening at sea

NASA satellite sees Sandra strengthening at sea [ Back to EurekAlert! ] Public release date: 8-Mar-2013
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Contact: Rob Gutro
Robert.j.gutro@nasa.gov
443-858-1779
NASA/Goddard Space Flight Center

Cyclone 19P in the Southern Pacific Ocean was renamed Sandra today, March 8, as NASA's Aqua satellite captured infrared data on the storm that indicated it would continue to strengthen. Residents of New Caledonia should prepare for impacts from Sandra early next week.

The Atmospheric Infrared Sounder (AIRS) instrument that flies aboard NASA's Aqua satellite captured an infrared image of Cyclone Sandra's cloud top temperatures on March 8 at 1717 UTC (12:17 p.m. EST). Strong thunderstorms around Sandra's center and in a band east of the center appeared as cold as -63 Fahrenheit (-52 Celsius), and are indicative of heavy rainfall.

As cloud tops grow taller in the troposphere, their temperatures grow colder (because temperatures drop with altitude in the troposphere). High cloud tops indicate a strong uplift of air that helps build the thunderstorms that make up a tropical cyclone. When uplift is strong, cloud tops sometimes punch through the top of the troposphere into the tropopause and even into the stratosphere.

Satellite imagery also showed central convection deepened (strengthened) over the storm's center since the previous day, indicating that Sandra is in a mode of strengthening.

Data from the Special Sensor Microwave Imager/Sounder (SSMIS) satellite instrument indicated an eye feature developing in Sandra early on March 8. Data from the SSMI is collected under the Defense Meteorological Satellite Program, which is a Department of Defense program responsible for designing, building, launching, and operating polar-orbiting environmental satellites.

On March 8 at 1200 UTC (7 a.m. EST/U.S.), Sandra's center was near 14.9 degrees south latitude and 157.7 degrees east longitude. The center of Cyclone Sandra was 645 nautical miles (742.3 miles/1,195 km) northwest of Noumea, New Caledonia. Sandra is moving to the east at 6 knots (7 mph/11.1 kph) and Sandra's maximum sustained winds had increased to near 60 knots (69 mph/111.1 kph).

Forecasters at the Joint Typhoon Warning Center noted on their update on March 8 that all environmental factors indicate that Sandra will continue to intensify over the next three days before weakening. Sandra is expected to pass west of New Caledonia on March 12, and bring heavy rain, possible flooding, strong winds and rough surf.

###


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


NASA satellite sees Sandra strengthening at sea [ Back to EurekAlert! ] Public release date: 8-Mar-2013
[ | E-mail | Share Share ]

Contact: Rob Gutro
Robert.j.gutro@nasa.gov
443-858-1779
NASA/Goddard Space Flight Center

Cyclone 19P in the Southern Pacific Ocean was renamed Sandra today, March 8, as NASA's Aqua satellite captured infrared data on the storm that indicated it would continue to strengthen. Residents of New Caledonia should prepare for impacts from Sandra early next week.

The Atmospheric Infrared Sounder (AIRS) instrument that flies aboard NASA's Aqua satellite captured an infrared image of Cyclone Sandra's cloud top temperatures on March 8 at 1717 UTC (12:17 p.m. EST). Strong thunderstorms around Sandra's center and in a band east of the center appeared as cold as -63 Fahrenheit (-52 Celsius), and are indicative of heavy rainfall.

As cloud tops grow taller in the troposphere, their temperatures grow colder (because temperatures drop with altitude in the troposphere). High cloud tops indicate a strong uplift of air that helps build the thunderstorms that make up a tropical cyclone. When uplift is strong, cloud tops sometimes punch through the top of the troposphere into the tropopause and even into the stratosphere.

Satellite imagery also showed central convection deepened (strengthened) over the storm's center since the previous day, indicating that Sandra is in a mode of strengthening.

Data from the Special Sensor Microwave Imager/Sounder (SSMIS) satellite instrument indicated an eye feature developing in Sandra early on March 8. Data from the SSMI is collected under the Defense Meteorological Satellite Program, which is a Department of Defense program responsible for designing, building, launching, and operating polar-orbiting environmental satellites.

On March 8 at 1200 UTC (7 a.m. EST/U.S.), Sandra's center was near 14.9 degrees south latitude and 157.7 degrees east longitude. The center of Cyclone Sandra was 645 nautical miles (742.3 miles/1,195 km) northwest of Noumea, New Caledonia. Sandra is moving to the east at 6 knots (7 mph/11.1 kph) and Sandra's maximum sustained winds had increased to near 60 knots (69 mph/111.1 kph).

Forecasters at the Joint Typhoon Warning Center noted on their update on March 8 that all environmental factors indicate that Sandra will continue to intensify over the next three days before weakening. Sandra is expected to pass west of New Caledonia on March 12, and bring heavy rain, possible flooding, strong winds and rough surf.

###


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-03/nsfc-nss030813.php

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Did Rand Paul change Obama?s drone policy? No.

This video frame grab provided by Senate Television shows Sen. Rand Paul, R-Ky. engaged in his filibuster on the??Whatever Republican Sen. Rand Paul tried to accomplish this week with his 13-hour filibuster of John Brennan's nomination to head the CIA, it had no immediate effect on President Barack Obama?s controversial drone war. And the overall impact of the tea party-aligned Kentucky lawmaker's audacious protest is still an open question.

Opinions vary widely on Paul's dramatic gesture. Did he take a heroic stand against Obama?s unconstitutional and outrageous assertion that he can target Americans on U.S. soil with deadly force like drone strikes without trial?

Or did he wage a pointless campaign to undermine the president?s power to combat terrorism while proving what we already knew: The U.S. government has neither the legal authority nor the inclination to rain missiles on your house just because your screen name is OBAMASUX and you once made a birth certificate joke online?

Paul's performance was the undeniable highlight of a debate that has shined an unusually bright light on Obama?s policy of targeting suspected terrorists overseas?including Americans?for assassination. (The media have boiled down that policy to its flashiest component: missile strikes from unmanned aerial vehicles, known as drones.)

But one thing seems clear: Paul's filibuster had no significant impact on the daily conduct of the drone war.

?Sen. Paul?s 13 hours on the Senate floor won?t have any practical effect on our policy and how we?re going after terrorists on a day-to-day basis,? a senior administration official told Yahoo News on condition of anonymity.

But didn?t Paul wring a letter out of Obama's top lawyer, Attorney General Eric Holder, in which he effectively promised that Americans who aren?t lining up to take a shot at the Capitol with a grenade launcher (to paraphrase the senator) are safe?

In a word: No.

During his 13 hours on the Senate floor, Paul repeatedly asked whether Obama believed he had the authority to kill an American, on U.S. soil, who was not ?actively attacking? America.

The question prompted Holder to respond.

?Dear Senator Paul,? Holder said in a 43-word letter. ?It has come to my attention that you have now asked an additional question: ?Does the President have the authority to use a weaponized drone to kill an American not engaged in combat on American soil?? The answer to that question is no.?

Holder didn't use the phrase ?actively attacking.? And administration officials privately agreed on Friday that ?not engaged in combat? was the key phrase going forward. None of them agreed to define the expression on the record.

Why the concern? Paul himself raised some of those questions in his filibuster.

?Will we use a standard for killing Americans to be that we thought you were bad, we thought you were coming from a meeting of bad people and you were in a line of traffic and so, therefore, you were fine for the killing?? he said. ?That is the standard we're using overseas. Is that the standard we're going to use here??

Holder?s letter doesn't answer that question. And observers from across the political spectrum made that point in the aftermath.

The filibuster drew bipartisan support. There was Republican Sen. Marco Rubio, with whom Paul could contend for the party?s 2016 presidential nomination. And there was Democratic Sen. Ron Wyden, who has pressed the administration for months to disclose its legal rationale for targeted killings.

The question now is whether Paul?s actions are part of a cresting tide of questions about those policies, or the high-water mark.

Overseas, drone strikes arouse deep public anger, notably in countries with large Muslim populations?much as the Iraq War did. A formal 2006 study by America?s intelligence community found that the Iraq invasion and occupation was creating terrorists faster than U.S. forces could take them out. It?s not clear whether the same thing could be happening with drones.

Administration officials said Obama wants to work with Congress to set some rules of the road when it comes to drones. They know that while the U.S. has a near-lock on their use today, it won?t be long before a rising power like China may acquire both the necessary technology and the willingness to use it.

?We must enlist our values in the fight,? Obama said in his State of the Union address. ?I recognize that in our democracy, no one should just take my word for it that we?re doing things the right way.?

He added, ?I will continue to engage Congress to ensure not only that our targeting, detention and prosecution of terrorists remains consistent with our laws and system of checks and balances, but that our efforts are even more transparent to the American people and to the world."

So where does Paul's filibuster fit in?

?It was a very public reminder that there are a lot of people out there, on both sides of the aisle, with questions about our operations and the legal analysis that underlies them,? the anonymous senior administration official explained. ?Senior U.S. officials have given speeches and testified and briefed on the Hill, the president has talked about it in the State of the Union, and you?ll see us continue to try to be more open about our policy when it comes to targeted operations.?

Source: http://news.yahoo.com/blogs/ticket/did-rand-paul-change-obama-drone-policy-no-224531093--politics.html

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Friday, March 8, 2013

Some brain cells are better virus fighters

Mar. 6, 2013 ? Viruses often spread through the brain in patchwork patterns, infecting some cells but missing others. New research at Washington University School of Medicine in St. Louis helps explain why. The scientists showed that natural immune defenses that resist viral infection are turned on in some brain cells but switched off in others.

"The cells that a pathogen infects can be a major determinant of the seriousness of brain infections," says senior author Michael Diamond, MD, PhD, professor of medicine. "To understand the basis of disease, it is important to understand which brain regions are more susceptible and why."

While some brain infections are caused by bacteria, fungi or parasites, often the cause is a virus, such as West Nile virus, herpesvirus or enteroviruses.

For their study, now available online in Nature Medicine, the researchers focused on granule cell neurons, a cell type that rarely becomes infected. They compared gene profiles in granule cells from the cerebellum with the activity in cortical neurons in the cerebral cortex, which are more vulnerable to infection.

The comparison revealed many differences, including a number of genes in cortical neurons that were less well-expressed -- meaning that for those specific genes there were fewer copies of mRNA, the molecules that relay genetic information from DNA to the cell's protein-making mechanisms.

Next, the researchers transferred individually 40 of those genes into cortical neurons and screened the cells for susceptibility to viral infection. The test highlighted three antiviral genes that are induced by interferon, an important immune system protein. When the expression level of these genes increased in cortical neurons, the cells' susceptibility to viral infection decreased.

The researchers also identified mechanisms that make some of these changes in genetic programming happen: regulatory factors known as microRNA, and differences in the way DNA is modified in the cell nucleus, both of which can affect gene expression levels.

Some of the genetic changes are only helpful against specific viral families, while others are effective against a broader spectrum of viruses and bacteria. The scientists can't say yet if the differences in infection susceptibility are driven by the need to prevent infection or if they are a byproduct of changes that help neurons in particular brain regions perform essential functions.

To learn more about how these innate immune genes help cells resist infection, Diamond and his colleagues are disabling them in the brains of mice.

Funding from the National Institutes of Health supported this research (U54 AI081680, the Pacific Northwest Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research; U19 AI083019l and R01 AI074973).

Cho H, Proll SC, Szretter KJ, Katze MG, Gale Jr. M, Diamond MS. Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses. Nature Medicine, online March 3, 2013.

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The above story is reprinted from materials provided by Washington University in St. Louis. The original article was written by Michael C. Purdy.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Hyelim Cho, Sean C Proll, Kristy J Szretter, Michael G Katze, Michael Gale, Michael S Diamond. Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses. Nature Medicine, 2013; DOI: 10.1038/nm.3108

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/WwEzVmZuUrM/130307091559.htm

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03/07/2013 - College of Arts and Sciences Dean For A Day

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